MERS

Priority List of Adverse events of special interest for

MERS

AESI: Pericarditis
Specific to MERS disease: ✅
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access

AESI: Thrombosis / Thromboembolism
Specific to MERS disease: ✅
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Hemorrhagic disease
Specific to MERS disease: ✅
Brighton Case Definition: End of 2023
Brighton CD Companion Guide: End of 2023


AESI: Thrombocytopenic Thrombosis Syndrome
Specific to vaccine: Adeno vectors
Brighton Case Definition: End of 2023
Brighton CD Companion Guide: End of 2023

AESI: Anaphylaxis
Specific to vaccine: All
vaccines
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Thrombocytopenia
Specific to vaccine: All
vaccines
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Vaccine-Associated Enhanced Disease
Specific to MERS disease: ✅
Brighton Case Definition: Click to access
Brighton CD Companion Guide:Click to access

AESI: Acute aseptic arthritis
Specific to vaccine: VSV vector
Brighton Case Definition: Click to access
Brighton CD Companion Guide: End of 2023


AESI: Rhabdomyolysis
Specific to COVID-19 disease: –
Specific to vaccine:
Brighton Case Definition: TBD
Brighton CD Companion Guide: TBD

AESI: Generalized convulsion
Specific to vaccine: All
vaccines
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Aseptic meningitis
Specific to vaccine: Live attenuated viral vaccine​
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Acute Disseminated Encephalomyelitis
Specific to MERS disease: ✅
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Encephalitis
Specific to MERS disease: ✅
Specific to vaccine: Live attenuated viral vaccine
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Myelitis
Specific to MERS disease: ✅
Specific to vaccine: Live attenuated viral vaccine
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Guillain Barré Syndrome
Specific to vaccine: Some vaccines¹
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access

AESI: Acute Respiratory Distress Syndrome
Specific to MERS disease: ✅
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access

AESI: Spontaneous abortion
Specific to MERS disease: ✅
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Mid 2023


AESI: Stillbirth
Specific to MERS disease: ✅
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Mid 2023


AESI: Maternal death
Specific to MERS disease: ✅
Brighton Case Definition: Click to access
Brighton CD Companion Guide: TBD


AESI: Neonatal death
Specific to MERS disease: ✅
Brighton Case Definition: Click to access
Brighton CD Companion Guide: TBD

1 Some seasonal influenza vaccines; monovalent H1N1 pandemic vaccine; COVID-19 ChAdOx-1 S vaccine.

Learn more about methods and results of the creation of the Priority List of potential Adverse events of special interest relevant to MERS vaccine trials HERE.

SEE ALL THE LISTS OF AESIs FOR THE CEPI PRIORITIZED PATHOGENS:

SEE ALL THE LISTS OF AESIs FOR THE CEPI PRIORITIZED PATHOGENS:

COVID-19
Chikungunya
Lassa Fever
Rift Valley Fever