Educational Resources
Educational resources from the SPEAC project for investigators, regulators, and public health professionals working in vaccine safety, including explainer videos, webinars, and training materials on AESIs, Brighton case definitions, and safety monitoring.
Featured Resource · New Overview Video
Preterm Birth as an Adverse Event of Special Interest (AESI)
Preterm birth, defined as live birth before 37 completed weeks of gestation, is an important outcome monitored in maternal immunization studies. This video introduces the Brighton Collaboration’s Global Alignment of Immunization Safety Assessment in Pregnancy (GAIA) case definition and considerations for standardized identification, classification, and reporting.
Topics covered
- Definition and classification of preterm birth
- Background rates by region
- Clinical pathways and risk factors
- Gestational-age assessment
- Levels of diagnostic certainty
- Standardized data collection and reporting
Core Learning Library
Short-form resources designed to support consistent understanding and application of key concepts, tools, and methods in vaccine safety.
Understanding Guillain-Barré Syndrome (GBS) and the Brighton Case Definition
Introduces Guillain-Barré syndrome, including its clinical presentation, and explains how the Brighton case definition supports consistent case classification and vaccine safety monitoring.
Watch video →What Is a Brighton Case Definition?
Explains how Brighton case definitions are structured and used to classify adverse events consistently across studies, settings, and vaccine safety surveillance systems.
Watch video →Case Definition Companion Guides
Provides an overview of how SPEAC Companion Guides support the consistent interpretation and application of Brighton case definitions in vaccine safety research.
Watch video →Automated Brighton Classification Tool Demonstration
Demonstrates how the Automated Brighton Classification Tool supports more efficient and standardized classification of adverse events using Brighton case definitions.
Watch video →What Is a Living Systematic Review?
Explains how living systematic reviews provide continually updated evidence to support vaccine safety monitoring, research, and decision-making.
Watch video →Webinar Recordings
Longer-form sessions and expert discussions exploring vaccine safety topics, methodologies, and practical applications in greater depth.
Sensorineural Hearing Loss, Lassa Fever, and Vaccines
Examines sensorineural hearing loss in the context of Lassa fever and vaccine development, including relevant clinical and vaccine safety considerations.
Watch recording →Background Rates for Observed–Expected Analysis
Explores how background rates are selected and applied in observed–expected analyses to support vaccine safety signal assessment and interpretation.
Watch recording →Evidence at Your Fingertips: Living Systematic Reviews
Provides a detailed look at how living systematic reviews support continuous evidence monitoring, synthesis, and decision-making in vaccine safety.
Watch recording →
