Rift Valley Fever

Priority List of Adverse events of special interest for

Rift Valley Fever

AESI: Myocarditis / Pericarditis
Specific to Rift Valley Fever disease: ✅
Specific to vaccine: MVA
Brighton Case Definition:  Click to access
Brighton CD Companion Guide: Click to access
AESI: Uveitis, retinitis, acute optic neuritis
Specific to Rift Valley Fever disease: ✅
Brighton Case Definition: NO
Brighton CD Companion Guide: NO
AESI: Hemorrhagic disease
Specific to Rift Valley Fever disease: ✅
Brighton Case Definition: NO
Brighton CD Companion Guide: NO


AESI: Thrombocytopenia
Specific to Rift Valley Fever disease: ✅
Specific to vaccine: All vaccines
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Thrombocytopenic Thrombosis Syndrome
Specific to Rift Valley Fever disease: ✅
Specific to vaccine: Adenoviral vectors
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Acute hepatitis / fulminant liver failure
Specific to Rift Valley Fever disease: ✅
Brighton Case Definition: NO
Brighton CD Companion Guide: NO
AESI: Anaphylaxis
Specific to vaccine: All vaccines
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access

AESI: Aseptic meningitis
Specific to vaccine: Live attenuated viral vaccine​
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Encephalitis
Specific to Rift Valley Fever disease: ✅
Specific to vaccine: Live attenuated viral vaccine
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Generalized convulsive seizure
Specific to Rift Valley Fever disease: ✅
Specific to vaccine: All vaccines
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Guillain Barré Syndrome
Specific to Rift Valley Fever disease: ✅
Specific to vaccine: Some vaccines¹
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access

¹Some seasonal influenza vaccines; monovalent H1N1 pandemic vaccine; COVID-19 ChAdOx-1 S vaccine.
AESI: Acute aseptic arthritis
Specific to vaccine: VSV vector
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
 

AESI: Acute kidney injury/renal failure
Specific to Rift Valley Fever disease: ✅
Brighton Case Definition: NO
Brighton CD Companion Guide: NO

1 Some seasonal influenza vaccines; monovalent H1N1 pandemic vaccine; COVID-19 ChAdOx-1 S vaccine.

Learn more about methods and results of the creation of the Priority List of potential Adverse events of special interest relevant to Rift Valley Fever vaccine trials HERE.

SEE ALL THE LISTS OF AESIs FOR THE CEPI PRIORITIZED PATHOGENS:

COVID-19
Chikungunya
Lassa Fever
Rift Valley Fever

SEE ALL THE LISTS OF AESIs FOR THE CEPI PRIORITIZED PATHOGENS:

COVID-19
Chikungunya
Lassa Fever
Rift Valley Fever