Brighton Collaboration Case Definitions
Brighton Collaboration Case Definitions are intended to:
Harmonize collection and analysis of vaccine safety data throughout the vaccine life cycle and across diverse resource settings.
Enable classifying cases across a range of diagnostic certainty from definite (level 1) to probable (level 2) to possible cases (level 3).
Provide a definition that can be applied equally to immunized and non-immunized individuals and thus are suited for use in:
- Determining background incidence of events of interest
- Causality hypothesis testing studies
Brighton Collaboration Case Definitions are not intended to guide clinical case management.
Learn more about the history Brighton Collaboration
Case definitions developed by SPEAC:
The list above is limited and only showing the CDs developed by the CEPI-funded SPEAC project. For those who want to have a ready link to all available CDs by pathogen or platform, they can access them via the AESI list section or see all the existing CDs using the button below.