Tools

SPEAC tools and resources

SPEAC develops tools for harmonized safety monitoring to support vaccine developers in vaccine studies of known epidemic and pandemic threats.

Brighton Collaboration Case Definitions

New Brighton Collaboration Case Definitions for AESIs that may occur with novel pathogens

Case Definition
Companion Guides

Resources and tools specific to events that have a published Brighton Collaboration Case Definition

List of Adverse Events of Special Interest (AESI)

Safety monitoring for COVID-19, Chikungunya, Lassa fever, MERS, Nipah, and Rift Valley Fever

Vaccine Templates

Standardized templates for benefit-risk assessments of new vaccine candidates

Guidance Documents

Guidance for data collection

LIVING SYSTEMATIC REVIEWS

Up-to-date, evidence-based information on emerging vaccines in pregnancy and childhood

Special Populations

Tools and Resources for Special Populations

CEPI Vaccine Safety Intelligence 

Centralized dashboard offering integrated, real-time insights into vaccine safety, immunization programs, and epidemic trends. Built in partnership with CEPI Vaccine Safety Coalition and Brighton Collaboration’s global network of experts.

Portal Tools

Automated Brighton Classification (ABC) Tool

Supports standardized classification of adverse events following immunization using Brighton Collaboration case definitions. The tool guides users through structured questionnaires and automatically determines the appropriate level of diagnostic certainty.

Active Surveillance LAndscape Tool

Interactive dashboard of systematically reviewed literature on active safety surveillance in low and middle income countries. 

All SPEAC tools and resources are also available on our Zenodo site