Evidence at Your Fingertips LSR Webinar

Evidence at your fingertips

Access real-time evidence for maternal and child vaccination

This page highlights a webinar demonstrating the Safe in Pregnancy / Safe in Children platform—an interactive hub that brings together real-time evidence through Living Systematic Reviews and meta-analyses on the safety, effectiveness, and immunogenicity of vaccines, with a focus on pregnant persons, children, and adolescents.

Registered participants will receive a calendar invite and a unique link to join the webinar.

Background

The Safe in Pregnancy / Safe in Children platform is an innovative, interactive hub that brings together real-time evidence through Living Systematic Reviews (LSRs) and meta-analyses on the safety, effectiveness, and immunogenicity of vaccines for pregnant persons, children, and adolescents. Health professionals, researchers, and decision-makers need quick, trustworthy access to evolving evidence to guide both policy and practice.

Objectives

Introduce the concept of Living Systematic Reviews and their value for vaccine safety and maternal–child health.
Demonstrate the main features of the Safe in Pregnancy / Safe in Children platform.
Provide practical, hands-on examples of how users can answer real-world clinical and policy questions through the platform.
Foster discussion on how continuous evidence synthesis can support immunization programs, NITAGs, and frontline health workers.

Target audience

Health professionals, especially those involved in maternal, neonatal, and child health
Health decision-makers and NITAG members
Researchers and academics in vaccine safety, clinical trials, and epidemiology
Students and trainees interested in evidence-based maternal and child health

Agenda (60 minutes)

Welcome & Introduction (5 min) – Flor Muñoz (framing the importance of rapid access to maternal–child vaccine evidence)
Why Living Systematic Reviews? (10 min) – Agustín Ciapponi (overview of LSRs and their role in global health decision-making)
Demo: Navigating Safe in Pregnancy (30 min)
- How to search for evidence by disease and population; how to interpret dashboards and outputs (10 min) – Mabel Berrueta
- Case study: Using Safe in Pregnancy to inform vaccination decisions (e.g., COVID-19, Chikungunya) (20 min) – Agustín Ciapponi & Agustina Mazzoni
Q&A and Next Steps (15 min) – Flor Muñoz (open discussion and invitation to engage with the platform)

Expected outcomes

Increased awareness of Safe in Pregnancy / Safe in Children as a global public good
Strengthened understanding of LSRs as tools for rapid evidence translation
Engagement of stakeholders who may incorporate the platform into teaching, decision-making, or guideline development
Raised awareness of the need for continuous monitoring of immunization safety and progress against emerging diseases with pandemic potential

Speakers & moderator

Agustín Ciapponi, MD, MSc, PhD

Director, Cochrane Argentina; IECS Global Evidence Synthesis Initiative (GESI)

Family physician and public health researcher specializing in systematic reviews and meta-analyses. Leads evidence synthesis initiatives at IECS and serves as Principal Investigator at CONICET and Assistant Professor at the University of Buenos Aires.

Agustina Mazzoni, MD, MSc

Obstetrician–Gynecologist; IECS Researcher

Obstetrician-gynecologist with postgraduate training in epidemiology and health policy management and 15+ years of experience in research and public health management, including participation in multinational maternal health trials and systematic reviews.

Mabel Berrueta, MD, MSc

Pediatrician, Neonatologist, Epidemiologist; IECS

Director of Mother and Child Health Research at IECS and coordinator of statistics/data management. Extensive experience leading multidisciplinary teams and clinical trials in maternal and child health, implementation research, infectious diseases, and living systematic reviews.

Flor Muñoz, MD, MSc

Moderator

Clinician-researcher with expertise in maternal immunization and vaccine safety. Facilitates discussion and audience Q&A during the session.

Webinar materials

Materials from this session, including the recording and presentation slides, will be posted here following the webinar.