Educational Resources
Educational resources from the SPEAC project for investigators, regulators, and public health professionals working in vaccine safety, including explainer videos, webinars, and training materials on AESIs, Brighton case definitions, and safety monitoring.
Understanding Guillain-Barré Syndrome (GBS) and the Brighton Case Definition
Guillain-Barré Syndrome, or GBS, is a rare but serious neurological disorder that can cause sudden muscle weakness or flaccid paralysis. This video provides a simple overview of what GBS is, how it presents, and why using a standard case definition is important for accurate diagnosis and vaccine safety monitoring.
Core Learning Library
Short-form resources designed to support consistent understanding and application of key concepts, tools, and methods in vaccine safety.
What Is a Brighton Case Definition?
Explains how Brighton case definitions are structured and used to classify adverse events consistently across studies and settings.
Watch videoCase Definition Companion Guides
Overview of how Companion Guides support consistent interpretation and application of Brighton case definitions.
Watch videoABC Tool Demonstration
Introduction to the Automated Brighton Classification tool for more efficient and standardized case classification.
Watch videoLiving Systematic Review (LSR) Explainer
Explains how living systematic reviews support continuous evidence monitoring relevant to vaccine safety.
Watch videoWebinar Recordings
Longer-form sessions and expert discussions exploring safety topics, methodologies, and use cases in greater depth.
SNHL, Lassa Fever, and Vaccines
Webinar on hearing-related safety considerations in vaccine trials.
Watch recordingBackground Rates for Observed–Expected Analysis
Explains how background rates are used in observed–expected analyses to support safety signal assessment.
Watch recordingLiving Systematic Review (LSR) Webinar
A deeper look at how living systematic reviews can be used in vaccine safety monitoring and evidence synthesis.
Watch recording
