Thrombosis with Thrombocytopenia Syndrome (TTS) and Vaccine-induced Immune Thrombocytopenia and Thrombosis (VITT)

AESI Case Definition Companion Guide

This document collates into a single document SPEAC resources (ICD-9/10-CM, MedDRA & SNOMED CT codes, background rates, risk factors, guidance (real time investigation, data collection, analysis and presentation) and tools (data abstraction & interpretation form, tabular summary of key case definition criteria and algorithms for level of certainty determination) for TTS and VITT. This guide can be used by stakeholders to assess the occurrence of TTS or VITT in several settings including as an adverse event following immunization.